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Don’t miss your opportunity to be a part of this event, now a highly anticipated Campbell tradition, a decade in the making!
More information at: library.campbell.edu/symposium2020
Osteopathic Medicine [clear filter]
Friday, March 27
 

08:00 EDT

[VIRTUAL] A Community-Based Investigation of Vaccine Perceptions and Hesitancy Within a Rural Community in North Carolina
Immunizations are one of the most effective methods in reducing morbidity, mortality, and healthcare costs associated with infectious diseases. Despite these benefits, recent outbreaks of vaccine preventable diseases have been associated with an increase in vaccine hesitancy—one of the top ten threats to global health (WHO). In this study, we identified factors that contribute to vaccine hesitancy among a rural population. Our results indicate that the highest levels of vaccine hesitancy center around the issue of confidence—a lack of trust in the safety and efficacy of vaccines, the health system that administers vaccines, and the motivations behind immunization policies.

LINK TO VIDEO PRESENTATION

Speakers
avatar for Meghan Nunnally

Meghan Nunnally

Class of 2024 Student, Campbell University School of Osteopathic Medicine

Mentors

Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Acute Liver Failure Due to Herpes Simplex Virus 1 and 2
A 65 year old male presented to the hospital with hypoglycemia and acute encephalopathy. He was found to have acute liver failure. His work-up revealed infection with both herpes simplex type 1 and 2 virus. What makes this case especially interesting is he also testes positive for influenza A. These are both uncommon causes of acute liver failure.



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Are Corpora Amylacea Protective Against Dementia in the Aging Brain?
Corpora amylacea (CA), beta amyloid plaques and neurofibrillary tangles are brain lesions commonly associated with dementia and aging. An uncertainty of the effects and causes of clinical presentations from these lesions still exists. In this study, we examine brains from cadavers with and without neurocognitive disease (ND) to investigate any existing associations between lesions found and the diagnosed cause of death. More specifically, we identify the location and number of corpora amylacea within the posterior temporal lobe and cerebellum at the level of the fourth ventricle. Brains with a cause of death due to ND were found to have less CA in the perivasculature and submeningeal areas when compared to brains that did not have neurocognitive disease. This study provides new insights on CA in the role of aging and ND. Due to the small sample size of this study more research would be needed to reinforce these findings.

Speakers
Mentors
avatar for Dr. Bonnie Brenseke, Chair of Biomedical Pathology

Dr. Bonnie Brenseke, Chair of Biomedical Pathology

Associate Professor of Pathology, Campbell University



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Cadaveric Case Study of Subdural Hematoma
A subdural hematoma (SDH) is defined as a collection of blood between the dura and arachnoid mater and is typically associated with brain injury. The resulting brain swelling and subdural hematoma both contribute to increased intracranial pressure. Hence, the cause of death in subdural hematoma is often brain herniation. The cause of death in this case was listed as subdural hematoma.



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Cadaveric Case Study: Atheroma with Granulation Tissue
Here we examine a 19mm arterial lesion of the left popliteal artery for atherosclerosis, which is defined as lipid accumulation in vessel walls. Plaques were graded for calcium deposition and granulation tissue. Granulation tissue in the arterial wall, and a thrombus in the popliteal artery lumen were discovered. We conclude that the cadaver likely suffered from advanced-stage atherosclerosis.

Speakers
avatar for Thomas S Davis

Thomas S Davis

OMS4, Campbell University School of Osteopathic Medicine
Thomas is a fourth-year medical student currently enrolled in the Campbell University Jerry M. Wallace School of Osteopathic Medicine. He will be graduating this May and pursuing residency in Internal Medicine with aspirations of pursuing a fellowship thereafter. He received his undergraduate... Read More →

Mentors


Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Cadaveric Case Study: Risk Factors and Sites of Metastasis of Esophageal Cancer
Esophageal cancer is among the most common and the sixth leading cause of cancer related death. During cadaveric dissection of a 77-year-old white male whose cause of death was listed as esophageal cancer, masses were found in the brain and adrenal gland. Histopathologic examination confirmed the masses to be EAC. Here we present a case of metastatic esophageal adenocarcinoma and discuss potential risk factors for tumor development.



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Cadaveric Study of Lipomatous Meningioma
A lipomatous meningioma is a rare variant of intracranial tumor that features adipose tissue deposition inside meningothelial cells. The pathway of meningeal cell metaplasia into adipose tissue has evaded researchers to this date. In this case study, a sample of this lipomatous meningioma was taken from a female human cadaver and visualized grossly as well as histologically with Hematoxylin & Eosin (H&E) stain. The comorbidities from this cadaver identified post-mortem were also reported. This case study contributes to the modest quantity of literature encompassing lipomatous meningiomas.



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Case Study of an Anomalous Accessory Muscle of the Posterior Forearm
We identified a supernumerary muscle of the extensor forearm compartment while dissecting a 90-year-old male cadaver. This muscle originated from a common origin site on the lower arm and inserted onto the thumb, just next to abductor pollicis longus. Previous reports noted similar supernumerary muscles, but none with this particular origin, insertion, or pathway. This muscle likely assisted with wrist and thumb abduction, but in being so superficial, may have posed an increased risk of developing pathological conditions. Alternatively, this muscle could be harvestable for reconstructive surgery, given its redundant function and possibility of being discovered during ultrasound.

LINK TO VIDEO PRESENTATION


Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Case Study of Uncommon Cystic Form of Nasal Polyp
A polypoid mass filled the nasal cavity of a 94-year-old man whose death was attributed to anorexia and failure to thrive. The purpose this study is to determine a diagnosis for the mass, and research causes and clinical implications. Microscopically, the mass was composed of numerous mucus-filled cysts lined by ciliated pseudostratified columnar epithelium. Histopathology is consistent with a chronic inflammatory type polyp; however, differences include a paucity of lymphocytes, a large cystic component, and loss of nasal bone. This uncommon form of nasal polyp may serve as a novel model of nasal polyp progression.

Speakers
Mentors
avatar for Dr. Bonnie Brenseke, Chair of Biomedical Pathology

Dr. Bonnie Brenseke, Chair of Biomedical Pathology

Associate Professor of Pathology, Campbell University



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Comparing Therapy and Treatment Options for Uterine Fibroids
Uterine fibroids are some of the most prevalent benign tumors in reproductive aged women. These tumors can cause unpleasant side effects including pelvic pain, bladder dysfunction, and even infertility. In previous decades hysterectomy was a typical treatment. Although still used today, less invasive treatments are also employed. Deciding on a treatment depends on several factors, such as cost effectiveness, age of patient, and recovery time. In this project we explore these influences within the scope of treatments available today.



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Design and Optimization of PCR-Based Assays to Test for Mitochondrial Transformation
Our group has developed a novel technique to modify the mitochondrial genome. Past work on this project has included synthesizing the vectors and developing transformation procedures. In this study, we continued to develop the transformation procedures, and designed and tested a PCR-based technique to assay for transformation. If successful, this could provide a tool to study many major diseases such as cancer, heart disease, and diabetes as well as provide a possible mechanism for mitochondrial gene therapy.



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Effects of Anthropometrics on Vertical Ground Reaction Force in Division 1 Athletes
The purpose of this study was to determine the relationship between an athlete’s anthropometrics (e.g., trunk length, tibial length, femur length) and peak vertical ground reaction force (vGRF). Participants (n=49 Division I athletes) stood on a 30 cm box and stepped onto the force plates followed by a maximum jump effort, landing back on the force plates. vGRF was moderately correlated with lean mass (r=.489), torso length (r=.398), and average tibial length (r=.289). Secondary analyses of jumpers vs non-jumpers showed that jumpers tended to jump higher, have lower percent body fat, and longer tibial length than non-jumpers.

Speakers
AT

Austin T. Vegas

Medical Student

Mentors


Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Efficacy and Implications of Ovarian Cystadenoma Diagnosis via Ultrasonography
This case study involves the investigation of an ovarian cystadenoma in a 79 year-old female cadaver. Histologic examination revealed classic features of a serous cystadenoma. It is of critical importance clinically to correctly differentiate between various benign masses. Classically, definitive diagnosis relies on histopathology, an invasive procedure. Alternatively, ultrasonography is less invasive and can be utilized to diagnose and monitor cysts, which can be distinguished from malignant ovarian neoplasms due to the lack of nodules. Conservative management of a benign cystadenoma is commonly recommended due to the high likelihood that it will resolve within two years or remain unchanged.



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Evaluating the Use of Mixed Reality to Teach Respiratory Anatomy
PURPOSE
To determine the feasibility and applicability of using mixed reality (MR) in medical anatomy instruction.
METHODS
First-year medical students were randomized into two groups: experimental group (learning activity with Microsoft HoloLens) and control group (learning activity with human cadavers and microscopes).
RESULTS
Both groups scored higher on post-activity assessment; there was no significant difference between groups. Compared to control group, experimental group had higher post-activity perceived histology understanding and rated the teaching method higher.
CONCLUSION
This study suggests teaching anatomy with MR is comparable to traditional methods of instruction and has potential to promote engagement and perceived understanding.

Speakers
Mentors
avatar for Dr. Bonnie Brenseke, Chair of Biomedical Pathology

Dr. Bonnie Brenseke, Chair of Biomedical Pathology

Associate Professor of Pathology, Campbell University



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Histopathology of Type I Papillary Renal Cell Carcinoma
The most common form of renal cancer is renal cell carcinoma (RCC), constituting 80-85% of renal cancer diagnoses. Renal cell carcinoma is delineated into various types, with the two most common being clear cell (87.7%) and papillary Type I and II (9.7%) . Type I and Type II papillary renal cell cancer differ slightly both histologically and clinically, and also have different prognostic implications for patients. The goal of this poster is to demonstrate our ability to classify RCC using histopathologic analysis, ultimately to afford better prognostic information and therapeutic choices for the patient and clinician.



Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Necrotizing Enterocolitis in a Full-term Infant: A Case Report and Review of Literature
This case demonstrates an uncommon presentation of necrotizing enterocolitis, a gastrointestinal emergency. Characterized by bacterial invasion, inflammation, and destruction of the bowel, necrotizing enterocolitis typically occurs in extremely preterm infants born at a gestational age less than 28 weeks. While less than fifteen percent of necrotizing enterocolitis cases occur in term infants, these cases are generally associated with other conditions such as congenital heart disease. This uncommon case of an otherwise healthy full-term infant presenting with bloody stools and diagnosis of necrotizing enterocolitis represents the importance of maintaining a broad differential diagnosis when evaluating neonates.

Speakers
Mentors


Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Non-inflammatory Gout in Interphalangeal Joints- A Case Study of a Cadaveric Specimen
Gout is an inflammatory condition due to the deposition of monosodium urate crystals in joints or soft tissues characterized by asymptomatic periods followed by brief painful, inflammatory flare-ups. This poster presents histologic findings from an 81 year old female cadaver with markedly enlarged joints of the hands that are suggestive of chronic tophaceous gout. Once a patient has reached this chronic stage, the disease is no longer painful due to the encapsulated tophi, supported by the lack of inflammation on the histological slides. However, the tophi also suggest that the individual experienced limited range of motion in the affected joints.

Speakers
avatar for Abby Daniels

Abby Daniels

Class of 2024 Student, Campbell University School of Osteopathic Medicine
avatar for Molly Kearney

Molly Kearney

OMS-I, Campbell University School of Osteopathic Medicine

Mentors


Friday March 27, 2020 08:00 - 17:00 EDT
Online

08:00 EDT

[VIRTUAL] Nuclear Autoantigenic Sperm Protein (NASP): A Possible Diagnostic Marker for Prostate Cancer
This project offers an exploration of a new line of diagnostic for prostate cancer. It is based on the aberrant expression of tNASP protein in prostate cancer cells. We examined the level of anti-tNASP antibodies in the sera of patients diagnosed with prostate cancer. Combined analysis of anti-tNASP and PSA tests demonstrated that 18.18% of PC patients with PSA higher than 4 ng/mL had a low level of anti tNASP antibody (false positive PSA, supported by negative biopsy); 9.1% of PC patients with PSA lower than 4 ng/mL had high levels of anti-tNASP antibodies (false negative PSA, proved histologically).



Friday March 27, 2020 08:00 - 17:00 EDT
Online
 
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