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A polypoid mass filled the nasal cavity of a 94-year-old man whose death was attributed to anorexia and failure to thrive. The purpose this study is to determine a diagnosis for the mass, and research causes and clinical implications. Microscopically, the mass was composed of numerous mucus-filled cysts lined by ciliated pseudostratified columnar epithelium. Histopathology is consistent with a chronic inflammatory type polyp; however, differences include a paucity of lymphocytes, a large cystic component, and loss of nasal bone. This uncommon form of nasal polyp may serve as a novel model of nasal polyp progression.