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Introduction: The ketogenic diet (KD) has been indicated to manage chronic seizures. With the development of newer anti-epileptic drugs (AED), little research has assessed AED carbohydrate composition impact on the KD.
Purpose: To evaluate the carbohydrate composition in common AEDs and their impact on pediatric KD adherence
Methods: Data were retrospectively collected and analyzed for drug carbohydrate content and effect on daily carbohydrate limits.
Results: Of 59 included patients, Topamax® had the greatest impact on drug carbohydrate limits whereas Keppra® had the smallest impact.
Conclusions: Medication carbohydrates should be considered when developing an AED regimen for patients on the KD.
