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Friday, March 27 • 09:00 - 17:00
Amantadine Induced Tremors and Hallucinations: A Pediatric Case Report

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Amantadine is being used in attention deficit hyperactivity disorder (ADHD) and in autism spectrum disorder (ASD) to treat symptoms of hyperactivity and irritability in children who do not respond to initial medication management. Amantadine is thought to work by preventing glutamate excitation and increasing dopamine. A 12-year-old male (36.2kg) with ADHD and ASD presented to Duke Children’s Hospital with tremulousness, altered mental status, hallucinations, increased seizure frequency and an elevated serum creatinine. This was his second admission for similar symptoms in a period of two weeks. Upon tapering off amantadine therapy, tremors and hallucinations resolved.


Friday March 27, 2020 09:00 - 17:00 EDT