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Friday, March 27 • 08:00 - 17:00
[VIRTUAL] Investigation of the Activity of Novel Compounds at the GPR6 Receptor

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Parkinson’s disease affects millions of people and has become the top 14th cause of death in the United States. Parkinson’s mainly affects dopamine-producing neurons that are involved with motor, visual, and various cognitive functions. In animal models, drugs for the orphan receptor GPR6 have been observed to help with managing symptoms brought on by Parkinson’s disease. For this study, novel ISR1 compounds purported to act at GPR6 were tested on cells to observe their effects on cell signaling molecules, beta-arrestin and cyclic AMP. These experiments will demonstrate whether these compounds act at GPR6, and might lead to new treatments for Parkinson’s Disease.

Friday March 27, 2020 08:00 - 17:00 EDT